Interests 

- Mechanism of reproductive disease

- Gene therapy for human disease
- Fat metabolism

- The mechanisms and roles of steroid hormones in human and animals

On going research 

- Effect of endocrine disruptors on the reproductive organs

- Mechanism of uterine contraction
- Signaling of steroid hormones

Education and Training

2012~ Present Professor, Department of Biomaterials Science, College of

Natural Resources & Life Science, Pusan National University, Korea

2011 Oct~2012 Aug Research professor, Lab of Biochemistry and Molecular biology, College

of Veterinary Medicine, Chungbuk National University, Chungju, Chungbuk,

Korea

2007~2011 Oct Post-doctoral fellow, Physiology department, Medical school

McGill University, Quebec, Canada

2002-2007 Ph. D, Reproductive and Developmental science

University of British Columbia, Vancouver, BC, Canada

2000~2002 M.S, Veterinary M olecular Biology and Biochemistry

College of Veterinary Medicine, Chungbuk National University, Chungju, Chungbuk, Korea

1993~2000 B.Sc, Veterinary medicine

College of Veterinary Medicine, Chungbuk National University, Chungju, Chungbuk, Korea

Awards and Honors

2011 Apr. Mcgill Med Star award

2010 9 28 Chosen as an Editor’s Choice by the Journal Science Signaling ( Sci. Signal. , 28 September 2010 Vol. 3, Issue 141, p. ec295 ), http://stke.sciencemag.org/cgi/content/abstract/sigtrans;3/141/ec295

2010-2011 Fonds de la recherch? en sant? post-doctoral fellowship (renewed)

2008-2010 Fonds de la recherch? en sant? post-doctoral fellowship

2007-2008 McGill University Health Centre post-doctoral fellowship award

2003-2007 Strategic Training Initiative in Research in Reproductive Health Sciences award

2006 University of British Columbia graduate external award

2005 University of British Columbia graduate external award

2004 Society for the Study of Reproduction (SSR) travel grant

2004 University of British Columbia graduate external award

2003 Division of Gynaecology Oncology Research travel award

2003 University of British Columbia graduate external award

2002 University of British Columbia Faculty of graduate studies international graduate scholarship

2000 충북대학교 수의학과 대학원과정 입학 수석

Peer-review ed publications (SCI Journals)

1. Kwack, S.J., Kwon, O., Kim, H.S., Kim, S.S., Kim, S.H., Sohn, K.H., Lee, R.D., Park, C.H., Jeung, E.B. & An, B. 2002, "Comparative evaluation of alkylphenolic compounds on estrogenic activity in vitro and in vivo", Journal of Toxicology and Environmental Health Part A, vol. 65, no. 5-6, pp. 419-431.

2. An, B., Kang, S.K., Shin, J. & Jeung, E. 2002, "Stimulation of calbindin-D< sub> 9k mRNA expression in the rat uterus by octyl-phenol, nonylphenol and bisphenol", Molecular and cellular endocrinology, vol. 191, no. 2, pp. 177-186.

3. An, B., Choi, K., Kang, S.K., Hwang, W.S. & Jeung, E. 2003, "Novel Calbindin-D< sub> 9k protein as a useful biomarker for environmental estrogenic compounds in the uterus of immature rats", Reproductive Toxicology, vol. 17, no. 3, pp. 311-319.

4. Lee, G., Choi, K., Park, S., An, B., Cho, M. & Jeung, E. 2003, "Expression of human Calbindin-D< sub> 9k correlated with age, vitamin D receptor and blood calcium level in the gastrointestinal tissues", Clinical biochemistry, vol. 36, no. 4, pp. 255-261.

5. Kim, I.H., Choi, K.C., An, B.S., Choi, I.G., Kim, B.K., Oh, Y.K. & Jeung, E.B. 2003, "Effect on abortion of feeding Korean pine needles to pregnant Korean native cows", Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, vol. 67, no. 3, pp. 194-197.

6. An, B., Choi, K., Kang, S.K., Lee, G., Hong, E., Hwang, W.S. & Jeung, E. 2003, "Mouse calbindin-D< sub> 9k gene expression in the uterus during late pregnancy and lactation", Molecular and cellular endocrinology, vol. 205, no. 1, pp. 79-88.

7. An, B., Choi, K., Lee, G., Leung, P.C. & Jeung, E. 2004, "Complex regulation of Calbindin-D< sub> 9k in the mouse placenta and extra-embryonic membrane during mid-and late pregnancy", Molecular and cellular endocrinology, vol. 214, no. 1, pp. 39-52.

8. Yun, S., Choi, K., Kim, I., An, B., Lee, G., Hong, E., Oh, G. & Jeung, E. 2004, "Dominant expression of porcine Calbindin ­ D9k in the uterus during a luteal phase", Molecular reproduction and development, vol. 67, no. 3, pp. 251-256.

9. An, B.S., Choi, K.C., Hong, E.J., Jung, Y.W., Manabe, N. & Jeung, E.B. 2004, "Differential transcriptional and translational regulations of calbindin-D9k by steroid hormones and their receptors in the uterus of immature mice", The Journal of reproduction and development, vol. 50, no. 4, pp. 445-453.

10. An, B., Choi, J., Choi, K. & Leung, P.C. 2005, "Differential role of progesterone receptor isoforms in the transcriptional regulation of human gonadotropin-releasing hormone I (GnRH I) receptor, GnRH I, and GnRH II", Journal of Clinical Endocrinology & Metabolism, vol. 90, no. 2, pp. 1106-1113.

11. Lee, S., Koo, B., Choi, J., Choi, D., An, B., Jeung, E. & Choi, I. 2005, "Degradation of bisphenol A by white rot fungi, Stereum hirsutum and Heterobasidium insulare, and reduction of its estrogenic activity", Biological & pharmaceutical bulletin, vol. 28, no. 2, pp. 201-207.

12. Kim, S.S., Lee, R.D., Lim, K.J., Kwack, S.J., Rhee, G.S., Seok, J.H., Lee, G.S., An, B.S., Jeung, E.B. & Park, K.L. 2005, "Potential estrogenic and antiandrogenic effects of permethrin in rats", The Journal of reproduction and development, vol. 51, no. 2, pp. 201-210.

13. Yeung, C.M., An, B.S., Cheng, C.K., Chow, B.K. & Leung, P.C. 2005, "Expression and transcriptional regulation of the GnRH receptor gene in human neuronal cells", Molecular human reproduction, vol. 11, no. 11, pp. 837-842.

14. An, B.S., Selva, D.M., Hammond, G.L., Rivero-Muller, A., Rahman, N. & Leung, P.C. 2006, "Steroid receptor coactivator-3 is required for progesterone receptor trans-activation of target genes in response to gonadotropin-releasing hormone treatment of pituitary cells", The Journal of biological chemistry, vol. 281, no. 30, pp. 20817-20824.

15. Poon, S.L., An, B., So, W., Hammond, G.L. & Leung, P.C. 2008, "Temporal recruitment of transcription factors at the 3 ′ , 5 ′ -cyclic adenosine 5 ′ -monophosphate-response element of the human GnRH-II promoter", Endocrinology, vol. 149, no. 10, pp. 5162-5171.

16. Park, S.H., Kim, K.Y., An, B.S., Choi, J.H., Jeung, E.B., Leung, P.C. & Choi, K.C. 2009, "Cell growth of ovarian cancer cells is stimulated by xenoestrogens through an estrogen-dependent pathway, but their stimulation of cell growth appears not to be involved in the activation of the mitogen-activated protein kinases ERK-1 and p38", The Journal of reproduction and development, vol. 55, no. 1, pp. 23-29.

17. An, B.S., Poon, S.L., So, W.K., Hammond, G.L. & Leung, P.C. 2009, "Rapid effect of GNRH1 on follicle-stimulating hormone beta gene expression in LbetaT2 mouse pituitary cells requires the progesterone receptor", Biology of reproduction, vol. 81, no. 2, pp. 243-249.

18. Chen, J., An, B., Cheng, L., Hammond, G.L. & Leung, P.C. 2009, "Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor- α contributes to fosB expression in mouse gonadotrophs", Endocrinology, vol. 150, no. 10, pp. 4583-4593.

19. Chen, J., An, B., So, W., Cheng, L., Hammond, G.L. & Leung, P.C. 2010, "Gonadotropin-Releasing Hormone-I-Mediated Activation of Progesterone Receptor Contributes to Gonadotropin α -Subunit Expression in Mouse Gonadotrophs", Endocrinology, vol. 151, no. 3, pp. 1204-1211.

20. Ball, R.W., Warren-Paquin, M., Tsurudome, K., Liao, E.H., Elazzouzi, F., Cavanagh, C., An, B., Wang, T., White, J.H. & Haghighi, A.P. 2010, "Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons", Neuron, vol. 66, no. 4, pp. 536-549.

21. Lamblin, M., Dabbas, B., Spingarn, R., Mendoza-Sanchez, R., Wang, T., An, B., Huang, D.C., Kremer, R., White, J.H. & Gleason, J.L. 2010, "Vitamin D receptor agonist/histone deacetylase inhibitor molecular hybrids", Bioorganic & medicinal chemistry, vol. 18, no. 11, pp. 4119-4137.

22. An, B.S., Tavera-Mendoza, L.E., Dimitrov, V., Wang, X., Calderon, M.R., Wang, H.J. & White, J.H. 2010, "Stimulation of Sirt1-regulated FoxO protein function by the ligand-bound vitamin D receptor", Molecular and cellular biology, vol. 30, no. 20, pp. 4890-4900.

23. Choi, K., An, B., Yang, H. & Jeung, E. 2011, "Regulation and molecular mechanisms of calcium transport genes: do they play a role in calcium transport in the uterine endometrium", J Physiol Pharmacol, vol. 62, no. 5, pp. 499-504.

24. Ahn, H., Yang, H., An, B., Choi, K. & Jeung, E. 2011, "Expression and regulation of Enpp2 in rat uterus during the estrous cycle", Journal of veterinary science, vol. 12, no. 4, pp. 379-385.

25. Jung, E., An, B., Choi, K. & Jeung, E. 2012, "Apoptosis- and endoplasmic reticulum stress-related genes were regulated by estrogen and progesterone in the uteri of calbindin-D(9k) and -D(28k) knockout mice", Journal of cellular biochemistry, vol. 113, no. 1, pp. 194-203.

26. Jung, E., An, B., Choi, K. & Jeung, E. 2012, "Potential estrogenic activity of triclosan in the uterus of immature rats and rat pituitary GH3 cells", Toxicology letters, vol. 208, no. 2, pp. 142-148.

27. Yang, H., Nguyen, T.T., An, B.S., Choi, K.C. & Jeung, E.B. 2012, "Synergistic effects of parabens on the induction of calbindin-D(9k) gene expression act via a progesterone receptor-mediated pathway in GH3 cells", Human & experimental toxicology, vol. 31, no. 2, pp. 134-144.

28. Jung, E., An, B., Yang, H., Choi, K. & Jeung, E. 2012, "Biomarker genes for detecting estrogenic activity of endocrine disruptors via estrogen receptors", International journal of environmental research and public health, vol. 9, no. 3, pp. 698-711.

29. Calderon, M.R., Verway, M., An, B.S., DiFeo, A., Bismar, T.A., Ann, D.K., Martignetti, J.A., Shalom-Barak, T. & White, J.H. 2012, "Ligand-dependent corepressor (LCoR) recruitment by Kruppel-like factor 6 (KLF6) regulates expression of the cyclin-dependent kinase inhibitor CDKN1A gene", The Journal of biological chemistry, vol. 287, no. 12, pp. 8662-8674.

30. Koo, T., Yang, H., An, B., Choi, K., Hyun, S. & Jeung, E. 2012, "Calcium transport genes are differently regulated in maternal and fetal placenta in the knockout mice of calbindin ­ D9k and ­ D28k", Molecular reproduction and development, vol. 79, no. 5, pp. 346-355.

31. Ahn, H., An, B., Jung, E., Yang, H., Choi, K. & Jeung, E. 2012, "Parabens inhibit the early phase of folliculogenesis and steroidogenesis in the ovaries of neonatal rats", Molecular reproduction and development, vol. 79, no. 9, pp. 626-636.

32. Kim, S., Jung, E., An, B., Hwang, I., Vo, T., Kim, S., Lee, S., Choi, K. & Jeung, E. 2012, "Additional effects of bisphenol A and paraben on the induction of calbindin-D (9K) and progesterone receptor via an estrogen receptor pathway in rat pituitary GH3 cells", J Physiol Pharmacol, vol. 63, no. 5, pp. 445-455.

33. Vo, T.T., An, B., Yang, H., Jung, E., Hwang, I. & Jeung, E. 2012, "C'albindin-D9k as a sensitive molecular biomarker for evaluating the synergistic impact of estrogenic chemicals on GH3 rat pituitary cells.", International journal of molecular medicine, vol. 30, no. 5, pp. 1233.

34. Salehi-Tabar, R., Nguyen-Yamamoto, L., Tavera-Mendoza, L.E., Quail, T., Dimitrov, V., An, B.S., Glass, L., Goltzman, D. & White, J.H. 2012, "Vitamin D receptor as a master regulator of the c-MYC/MXD1 network", Proceedings of the National Academy of Sciences of the United States of America, vol. 109, no. 46, pp. 18827-18832.

35. Kim, J.E., Choi, S.I., Lee, H.R., Hwang, I.S., Lee, Y.J., An, B.S., Lee, S.H., Kim, H.J., Kang, B.C. & Hwang, D.Y. 2012, "Selenium significantly inhibits adipocyte hypertrophy and abdominal fat accumulation in OLETF rats via induction of fatty acid β -oxidation", Biological trace element research, vol. 150, no. 1-3, pp. 360-370.

36. Yang, H., Choi, K., Jung, E., An, B., Hyun, S. & Jeung, E. 2013, "Expression and Regulation of Sodium/Calcium Exchangers, NCX and NCKX, in Reproductive Tissues: Do They Play a Critical Role in Calcium Transport for Reproduction and Development?" in Sodium Calcium Exchange: A Growing Spectrum of Pathophysiological Implications Springer, , pp. 109-121.

37. Kim, S., An, B.S., Yang, H. & Jeung, E.B. 2013, "Effects of octylphenol and bisphenol A on the expression of calcium transport genes in the mouse duodenum and kidney during pregnancy", Toxicology, vol. 303, pp. 99-106.

38. Jung, E., An, B., Kim, Y., Hwang, I., Lee, J., Shin, T., Hyun, S., Hwang, W. & Jeung, E. 2013, "Establishment of transgenic fibroblasts for producing recombinant human interferon- α and erythropoietin in bovine milk", Molecular medicine reports, vol. 7, no. 2, pp. 406-412.

39. An, B., Kang, J., Yang, H., Yang, M. & Jeung, E. 2013, "Effects of Acer okamotoanum sap on the function of polymorphonuclear neutrophilic leukocytes in vitro and in vivo", Molecular medicine reports, vol. 7, no. 2, pp. 654-658.

40. Hwang, I., An, B., Yang, H., Kang, H., Jung, E. & Jeung, E. 2013, "Tissue-specific expression of occludin, zona occludens-1, and junction adhesion molecule A in the duodenum, ileum, colon, kidney, liver, lung, brain, and skeletal muscle of C57BL mice", J Physiol Pharmacol, vol. 64, no. 1, pp. 11-18.

41. Yang, H., An, B., Choi, K. & Jeung, E. 2012, "Change of Genes in Calcium Transport Channels Caused by Hypoxic Stress in the Placenta, Duodenum, and Kidney of Pregnant Rats 1", Biology of reproduction, vol. 88, no. 2.

42. Yang, H., Kim, T., An, B., Choi, K., Lee, H., Kim, J. & Jeung, E. 2013, "Differential expression of calcium transport channels in placenta primary cells and tissues derived from preeclamptic placenta", Molecular and cellular endocrinology, vol. 367, no. 1, pp. 21-30.

43. Lee, Y.J., Kim, J.E., Hwang, I.S., Kwak, M.H., Lee, J.H., Jung, Y.J., An, B.S., Kwon, H.S., Kim, B.C. & Kim, S.J. 2013, "Alzheimer's phenotypes induced by overexpression of human presenilin 2 mutant proteins stimulate significant changes in key factors of glucose metabolism", Molecular medicine reports, vol. 7, no. 5, pp. 1571-1578.

44. Verway, M., Bouttier, M., Wang, T.T., Carrier, M., Calderon, M., An, B.S., Devemy, E., McIntosh, F., Divangahi, M., Behr, M.A. & White, J.H. 2013, "Vitamin D induces interleukin-1beta expression: paracrine macrophage epithelial signaling controls M. tuberculosis infection", PLoS pathogens, vol. 9, no. 6, pp. e1003407.

45. An, B., Kang, J., Yang, H., Jung, E., Kang, H., Choi, I., Park, M. & Jeung, E. 2013, "Anti-inflammatory effects of essential oils from Chamaecyparis obtusa via the cyclooxygenase-2 pathway in rats", Molecular medicine reports, vol. 8, no. 1, pp. 255-259.

46. Dimitrov, V., Salehi-Tabar, R., An, B. & White, J.H. 2013, "Non-classical mechanisms of transcriptional regulation by the vitamin D receptor: Insights into calcium homeostasis, immune system regulation and cancer chemoprevention", The Journal of steroid biochemistry and molecular biology, .

47. Kwak, M.H., Kim, J.E., Hwang, I.S., Lee, Y.J., An, B.S., Hong, J.T., Lee, S.H. & Hwang, D.Y. 2013, "Quantitative evaluation of therapeutic effect of< i> Liriope platyphylla on phthalic anhydride-induced atopic dermatitis in IL-4/Luc/CNS-1 Tg mice", Journal of ethnopharmacology, vol. 148, no. 3, pp. 880-889.

48. An, B., Ahn, H., Kang, H., Jung, E., Yang, H., Hong, E. & Jeung, E. 2013, "Effects of estrogen and estrogenic compounds, 4-tert-octylphenol, and bisphenol A on the uterine contraction and contraction-associated proteins in rats", Molecular and cellular endocrinology, vol. 375, no. 1, pp. 27-34.

49. Jung, E., An, B., Kim, Y., Jeong, Y., Hwang, W. & Jeung, E. 2013, "Generation of porcine fibroblasts overexpressing 11 β? HSD1 with adipose tissue ? specific aP2 promoter as a porcine model of metabolic syndrome", Molecular medicine reports, vol. 8, no. 3, pp. 751-756.

50. Hwang, I., Yang, H., Kang, H., Ahn, C., Hong, E., An, B. & Jeung, E. 2013, "Alteration of Tight Junction Gene Expression by Calcium-and Vitamin D-Deficient Diet in the Duodenum of Calbindin-Null Mice", International journal of molecular sciences, vol. 14, no. 11, pp. 22997-23010.

51. Kim, J., Ahn, H., Han, B., Lee, S., Cho, Y., Kim, C.H., Hong, E., An, B., Jeung, E. & Lee, G. 2014, "Korean Red Ginseng Extracts Inhibit NLRP3 and AIM2 Inflammasome Activation", Immunology letters, .